Sentence examples for mutations that underlie from inspiring English sources

We present a new approach to estimate the rate and selective advantage of beneficial mutations that underlie the adaptation of asexual populations.

A congenic breeding strategy has also been employed extensively in laboratory rats because it is now possible to map the genetic variants and mutations that underlie complex disease-related phenotypes in this species [18], [19].

In this transgenic mouse strain, in agreement with findings in other mouse models of AD with distinct genetic mutations that underlie their pathology [22], [23] we have found a decreased neurogenesis in the SGZ of the hippocampus.

Discovering novel mutations that underlie monogenetic disorders associated with Candida infections by GWAS or deep sequencing.

An interesting feature of the missense mutations that underlie KID syndrome is that they are dominant.

However, the mutations that underlie such QTL have been identified only in a few cases [ 1].

Where they differ is on the likelihood of identifying one key mutation that underlies a given cancer.

We illustrate the power of the general approach by showing how genetically engineered mouse models can define the precise signaling pathways that are affected by the gain-of-function mutation that underlies Noonan syndrome.

Results In this study, the authors used whole-genome sequencing to map a new CLCN7 mutation that underlies a recessively inherited, severe form of osteopetrosis in Belgian Blue cattle.

At a session yesterday, she learned how researchers are using sequencing tools to reveal new mutations that may underlie cancer.

We also discuss the various types of mutations that might underlie this fatal neurodegenerative condition and outline some of the strategies that might be useful in untangling them.