Sentence examples for mutations that suppress from inspiring English sources

Long-lived dwarf mouse strains carry mutations that suppress the growth hormone (GH /insulin-like GH /insulin-like(Igrowthendocrine pathway [ 1].

It will be very interesting to determine whether mutations that suppress the adverse effects of aneuploidy also delay aging and extend the span and quality of life.

Improved sperm quality in the polygamous lines may have been driven by directional selection on standing genetic variation, and/or via the removal of deleterious mutations that suppress sperm quality [ 12].

We reasoned that screening for loss-of-function mutations that suppress the dauer-constitutive phenotype of eak-7 ; akt-1 double mutants might identify genes encoding novel DAF-16/FoxO activators.

To identify second-site mutations that suppress the tpp1− developmental phenotype in the presence of chloroquine, we mutagenized cells using restriction enzyme-mediated integration (REMI) mutagenesis (Kuspa, 2006) and examined the development of mutant clones in the presence of chloroquine.

Previously, we have identified 13 seizure-suppressor mutations that suppress the BS behavioral phenotypes of sda and eas mutants, and raise the electrophysiology seizure threshold, often to nearly wild-type levels (reviewed in Parker et al. 2011b).

Since, prior to this study, only five Su TPE) loci were known and we had only been able to identify two additional Su TPE) from our analysis of Su var)s and two from our analysis of the Su z 25 deletion, we undertook a screen designed to identify mutations that suppressed TPE.

To identify genes acting with IAR1 to control conjugate sensitivity, we conducted a genetic modifier screen to isolate extragenic mutations that suppressed the iar1 mutant phenotype.

Ninety-seven percent of mutations that suppressed mot1-301 expression were in genes that encode components of the SUMO pathway (Wang et al. 2006), and mutations in every step of the SUMO pathway suppressed mot1-301.

Following a previously-published protocol (Chai et al., 2010), we set up a genetic screen to search for spontaneous mutations that suppressed the defective biofilm phenotype of a B. subtilis ΔslrR mutant (YC131).

Second, Li and colleagues recovered less than 0.1% (50 out of ~150,000) of snc1 M2 plants carrying recessive mutations that suppressed snc1-dependent phenotypes, while more than 10% of bal M2 plants showed non-parental morphology in our experiments [ 9, 14].