Sentence examples for mutations that show from inspiring English sources

For LRRK2, there are a number of mutations that show clear evidence of segregation.

Familial conditions are usually caused by autosomal dominant mutations that show a variable degree of expressivity.

But, these tools consistently fail in correctly annotating laboratory-induced mutations that show no functional impact in the laboratory assays.

In addition, eight mutations that show very fast kpep values and thus suppress the effect of the hyperstable Tyr-T1 tRNATyr are all proteins that substantially weaken binding to aa-tRNA (ΔΔ Go > 0.6 kcal/mol).

However, we find that the majority of pedigrees in which patients exhibit reproducibly short disease durations are associated with mutations that show a high inherent propensity to induce aggregation of SOD1.

But there are multiple other cases of globin gene mutations that show the same kind of pattern, and it is unlikely that this hypothesis applies to all of them (indeed, Flint et al. do not attempt a general explanation, and others do not think that conversion really applies to HbS [ 234]).

For example, we identified 5 mutations that showed normal immediate memory, but abnormal short-term memory, the memory profile we obtained in our primary screen for mice with hippocampal lesions.

By partially resequencing genes, we identified four candidates containing six mutations that showed a strong association with the target phenotype.

To be conservative in our method of identifying CI, we only considered mutations that showed molecular evolutionary evidence of being adaptive (criteria described in Table 3 and Discussion).

First, we selected C408G, a mutation found in one of the original DC families with hTR mutations that showed a 75% decrease in levels of observed telomerase catalytic activity (26).

Genes with non-synonymous point mutations that showed significant POLYPHEN (>0.5) or SIFT scores (>0.1) were compared to the 'Breast Invasive Carcinoma, TCGA 2012' and 'TCGA provisional' databases to determine the frequencies in patient cohorts.