Sentence examples for mutations that reside from inspiring English sources

This study focuses on a collection of 19 mutations that reside in 13 genes (see Results).

First, we show that tumor subpopulations can be spatially segregated in the tumor and carry distinct sets of somatic mutations that reside in different geographical regions.

This could suggest a dominant-negative mechanism, as was demonstrated by Scott et al (2002); some missense mutations that reside outside the PI3-K region have an effect on ATM downstream targets by a dominant-negative mechanism.

Two of these are point mutations that reside in the catalytic gorge of the enzyme [ 6] and a third one is a small deletion located in the carboxyl-terminal of the enzyme [ 7, 8].

Variants were further filtered for "functional" coding mutations that result in a change in the amino acid sequence (i.e. missense/nonsense), or mutations that reside within a putative splice site junction (with a window size of 7, as supplied in the parameter for SNPeff).

We also identified a large number of private mutations that resided in minor tumor subpopulations and were not shared by the neighboring tumor cells.

At reproduction, the number of gametes produced by the hybrids corresponds to their relative fitness compared to the other hybrids but the gametes contain only the mutations that resided on the clonally transmitted part of the parents' genome.

84 out of the 89 mutations that were identified reside in protein-coding regions (Table 1).

However, the analysis also flags mutations that do not reside within conserved domains, such as the G98E mutation, which is found in the region between the highly conserved MH1N and MH1C domains.

Also, the three mutations that resided outside predicted domains were scored as deleterious by one to all four in silico programs.

We used a transposon insertion mutation (P{EP}G6528) that resides within the protein coding sequence of cisd2 exon 1 (http://flybase.org) to further address the possibility that cisd2 influences the effects of Ppt1 overexpression in the eye.