Sentence examples for mutations that represented from inspiring English sources

These cut-off values were also dependent on the number of reads, but resistance mutations that represented on average 0.05% (range 0.014 0.29%) and viral variants that represented on average 0.11% (range 0.09 0.21%) were high-confidence, i.e. exceeded our statistically derived cut-off values.

In addition the Sequenom platform is more sensitive than Sanger sequencing in that it was able to detect mutations that represented only 5% of the DNA.

Binding measurements of 85RF45.1 Fab to Pfs48/45 6C constructs possessing single point mutations that represent these polymorphisms revealed that the antibody is still capable of binding its epitope with nanomolar affinity (Fig. 4c).

We applied a robust technique developed in [9] to the 672 sequences which identified all robust mutations in the data using Principal Component Spectral Analysis [10], [18] [21] to identify the mutations that represent most of the variation in the data.

During the course of the candidate screen, we examined 90 point mutations that represent a minimum of 43 different loci (summarized in Table 6), and 85 deficiencies representing 52 candidate loci (summarized in Table 7).

In general, it is desirable to include samples containing mutations that represent the range of possible variation in parameters that are important to the technique under test.

Lastly, in the future, with next-generation DNA sequencing techniques, it may become possible to detect the presence of secondary mutations that represent a very small fraction of cells at initial presentation.

A critical challenge in the genome-wide analysis of CNAs is to distinguish between the "driver" mutations that allow the tumor to initiate, grow, and persist, and the "passenger" mutations that represent random somatic events accumulated during tumorigenesis [ 1, 3, 7].

In clinical samples with some assays it was possible to detect mutations that only represented 5% of the total 2 peak areas.

Second, mutations that are represented with an amino acid information were converted into those with a genomic location using the exon and intro information in Consensus CDS (CCDS, using GRCh37.p13) [ 16- 18] so that we could observe the differences between LoF and GoF mutations at the nucleotide sequence level.

(P_{M}) Probability of mutation operator that represents the number of chromosomes mutating in each iteration of algorithm.