Sentence examples for mutations that predispose from inspiring English sources

A Utah firm, Myriad Genetics, had isolated two human genes, BRCA1 and BRCA2, that can contain mutations that predispose women who carry them to breast cancer — crucial knowledge for early detection and prevention.

The patents cover two genes, BRCA1 and BRCA2, and the over $3,000 analysis Myriad performs on the genes to see if women carry mutations that predispose them to breast and ovarian cancers.

It plans to cull these variations to find patterns of particular mutations that predispose patients to major killers such as heart failure, as well as genetic alterations that increase the risk of side effects from prescription drugs.

It plans to cull these variations to find particular mutations that predispose patients to major killers and also to genetic alterations that increase the risk of side effects from prescription drugs.

In addition to BRCA1 and BRCA2, there are dozens of other mutations that predispose women to these and other cancers.

This is also important, as whole-genome association studies have identified mutations that predispose to hypertension that link to the SPAK gene and increase SPAK expression [ 33].

Von Hippel-Lindau (VHL) is an autosomal dominant disease caused by VHL gene mutations that predisposes individuals to central nervous system hemangioblastomas, renal cysts, renal cell carcinoma, pancreatic cysts, retinal angiomas, and pheochromocytomas (Fig. 1).

Living in the shadow of her mother's death at 49 from breast cancer, and the discovery she also carries the genetic mutation that predisposes her to the disease, she sets about finding statistical and anecdotal evidence to help inform her choice.

However, although noncarriers do not have a BRCA1/2 mutation that predisposes them to breast/ovarian cancer at a younger than expected age, they are still at population risk.

This study thus documents the inheritance of a germline INI1-mutation that predisposes to the development of MBTs at young age in three subsequent generations of a family.

Our knowledge of specific mutations that may predispose response to other agents is, however, formative and further evaluation is required.