This again illustrates the potential of WGS to identify co-occurring mutations that pose genetic risks beyond the patient's primary diagnosis or that may be modifiers of cancer risk.
Given the breadth of MPS gene interrogation, it is reasonable to anticipate that occasional participants may have mutations that pose a likely severe negative consequence, which we classify as "panic" results.
Imatinib-resistant advanced GIST continues to pose a therapeutic challenge, likely due to the frequent presence of multiple mutations that confer drug resistance.
Finally, cancer genome sequencing poses a particular difficulty in this respect, as the disease is caused by somatic mutations that may occur in a multitude of locations.
That poses another $8 billion drag.
But even that poses challenges.
Mutations that add or change function?
Somewhere among the genetic disparities must lie the mutation or, more probably, mutations that define us.
That poses a concern for the Yankees.
That poses all kinds of challenges".
