Your English writing platform
Discover LudwigSuggestions(1)
Exact(1)
And Roden points to a new wave of studies that are finding very rare mutations that more dramatically raise or lower risk.
Similar(59)
The authors also find that mutations that confer more resistance tend to be more costly.
Although we observed them during the melting process after 30 and after 40 cycles, a larger amount of the product is more beneficial for small mutations that are more difficult to distinguish after the 30th cycle.
In contrast to Keio mutants, transposon insertion can generate mutations that inactivate more than one gene (e.g., a full operon) and, more importantly, mutations that affect genes at different levels (e.g., mutants that modulate gene expression by insertions in promoter regions [ 26], or mutants with partial gene activity by insertions near the C-terminus of a gene).
Our approach also allowed us to identify 1652 total mutations (including recurrent mutations that occurred more than once per mouse), permitting clonal expansion correction and making the assay 50%% more sensitive in detecting increases in mutation frequencies.
3, 41, 42 It could also be argued that suspected Lynch syndrome colorectal cancer cases carry undetected mutations associated with a more moderate penetrance of cancer compared with that of exonic and splice site mutations that are more readily detected.
Now, researchers have found a handful of DNA mutations that arise more frequently in patients with the disorder.
Researchers had hoped a close look at virus isolates from the pigs would clarify matters, but new sequences posted on a public database yesterday had many unusual mutations that raised more puzzling questions.
Major cancer sequencing initiatives have therefore focused on recurrent mutations that are more likely to be drivers.
While mutation hotspots are expected to reveal oncogenes, tumor suppressors are generally targeted by mutations that are more distributed over the gene in cancer.
This is especially relevant for PH1 missense mutations that are more destabilized in their apo-form than in their holo-form.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com