Sentence examples for mutations that leads from inspiring English sources

Another class of mutations that leads to modest activation is found in the ATP-binding glycine-rich loop.

On the other hand, switching drugs too late allows the accumulation of mutations that leads to multidrug resistance [ 2, 3].

Often, however, it is not a single mutation, but rather a non-linear combination of different mutations that leads to drug resistance.

The last of the nine changes identified by deep-sequencing was a C-T transition (typical for EMS-induced mutations) that leads to a threonine to methionine change in CG12414 and is present only in rye mutants.

The L858F mutation in NaV1.7 is one of the best characterized and most common gain-of-function mutations that leads to PEM and is associated with a severe phenotype (Han et al., 2007; Samuels et al., 2008; Cheng et al., 2011; Segerdahl et al., 2012).

Further studies are required to determine which gene or genes are mutated and how the mutations that led to their inactivation were selected for in the first place.

Perhaps, most importantly, chromosome replacement therapy could correct the accumulating genetic damage and mutations that lead to ageing in every one of our cells.

Pooled data are also needed to understand mutations that lead to rare diseases in children, Dr. Altshuler said.

We need some UV light to penetrate our skin to make vitamin D, but UV light also causes mutations that lead to cancer, requiring a different balance for different levels of sunlight exposure.

A negative test result may provide a false sense of security, since not all inherited mutations that lead to cancer are known.

Although tests are being developed and in some cases are available to detect mutations that lead to those cancers, much controversy surrounds their use.