Sentence examples for mutations that lack from inspiring English sources

Here, we demonstrate that immature/transitional 1 B cells from the bone marrow of CD154-deficient mice express AID and acquire Ig mutations that lack the hallmarks of antigenic selection via BCR signaling.

Recently, two separate groups examined transgenic mice with CD40 mutations that lack one or both TRAF binding sites [14], [15].

These multiple structural requirements limit the opportunities for creation of mutations that lack diphthamide while retaining function in protein synthesis.

In contrast, the deletion mutations that lack the C-terminal tail do not interact with DPP signaling in embryos or wings.

It does not include mutations that lack phenotypic consequences.

Steric effects like HER2 mutations that lack the extracellular domain or have internal domain mutations are another mechanism.

In turn, the mouse with a CC2D1A mutation that lacks all but the first DM14 has an even more severe phenotype causing death shortly after birth [ 17].

Apart from the R1874stop mutation that lacks the kinase domain and is therefore inactive, all other mutants tested possessed similar activity to wild-type LRRK2.

By comparing growth properties of synthetic viruses with synonymous 125G mutations that were lacking the novel splice site, we were able to demonstrate that the observed increases in viral growth was primarily due to the novel splice product of the NS gene, and not due to the D125G amino acid change in the NS1 protein that resulted in decreased replication in M1 and MDCK cells.

Worms given life-span-enhancing mutations produce offspring that lack the responsible genes but live longer anyway.

This is expected if sterile mutations occur in populations that lack variation in fitness.