Sentence examples for mutations that introduced from inspiring English sources

Such cases can be explained by post-formational mutations that introduced new alleles to a line, but with insufficient time having subsequently transpired for the completion of allelic segregation to homozygosity.

The co-expression of mutations that introduced additional cysteine residues into the extracellular domain can result in disulphide bond formation between adjacent subunits when the introduced residues are sufficiently close and in the correct orientation.

There were no deletions or insertions in any of the amplified gene fragments and no mutations that introduced premature stop codon that would generate a truncated protein.

We note that, in general, the changes in activity for the mutants listed in Table 1 were due to a decrease in kcat values and that mutations that introduced steric clashes also demonstrated increases in KM.

Mutations that introduced a termination codon into IRF6 were found to be significantly more common in VWS than in PPS consistent with haploinsufficiency being the mechanism that underlies VWS (20, 22, 26).

- Worked with Professor Phillip Geissler and Dirk Trauner to model photo-isomerizable tethered ligands in order to design tethers and corresponding mutations that introduce photo-switchable behavior into target proteins.

We have predicted mutations that introduce triose phosphate isomerase activity into ribose-binding protein, a receptor that normally lacks enzyme activity.

This variant might be included in the above-described category of mutations that introduce proline residues.

Previous studies have identified several mutations that introduce abnormal morphology and volume.

These activating mutations are missense mutations that introduce amino-acid substitutions mainly at positions 12, 13 and 61.

The putative complete ORF in OY-M is disrupted by single base mutations that introduce two additional in-frame stops.