Sentence examples for mutations that introduce from inspiring English sources

- Worked with Professor Phillip Geissler and Dirk Trauner to model photo-isomerizable tethered ligands in order to design tethers and corresponding mutations that introduce photo-switchable behavior into target proteins.

We have predicted mutations that introduce triose phosphate isomerase activity into ribose-binding protein, a receptor that normally lacks enzyme activity.

Conversely, most mutations that introduce a new function are destabilizing [19], [20].

Previous studies have identified several mutations that introduce abnormal morphology and volume.

This variant might be included in the above-described category of mutations that introduce proline residues.

Six mutations that introduce a PTC into the human ZIC3 transcript have been associated with congenital defects.

Such cases can be explained by post-formational mutations that introduced new alleles to a line, but with insufficient time having subsequently transpired for the completion of allelic segregation to homozygosity.

There were no deletions or insertions in any of the amplified gene fragments and no mutations that introduced premature stop codon that would generate a truncated protein.

The co-expression of mutations that introduced additional cysteine residues into the extracellular domain can result in disulphide bond formation between adjacent subunits when the introduced residues are sufficiently close and in the correct orientation.

We note that, in general, the changes in activity for the mutants listed in Table 1 were due to a decrease in kcat values and that mutations that introduced steric clashes also demonstrated increases in KM.

Mutations that introduced a termination codon into IRF6 were found to be significantly more common in VWS than in PPS consistent with haploinsufficiency being the mechanism that underlies VWS (20, 22, 26).