Sentence examples for mutations that interact from inspiring English sources

The ico locus was identified in suppressor and enhancer screens for mutations that interact with TGF-beta signaling.

In a genetic screen for mutations that interact with an activated form of the TGF-beta type I receptor Thick Veins (TKV), we isolated several genes that suppressed the growth and pattern defects of excess TKV signaling in wings [8], [9].

In particular, we identify second-site mutations that interact with para bss1, seizure enhancers, and seizure suppressors.

Here, we identify a derived haplotype with two mutations that interact epistatically to increase binding affinity for the MSL complex.

We identified two different types of mutations that interact with the opus insertion to increase the severity of the variable dorsalization.

The evolution of maternally transmitted organelles can lead to SC when mitochondrial mutations that interact epistatically with nuclear genes have favorable effects in females but are deleterious in males (Rice 1984; Rice et al. 2006; Vicoso and Charlesworth 2006).

For example, a binding site mutation that interacts directly with the drug molecule might confer primary drug resistance [ 13- 15].

However, MUS81 mutations that do not interact with SLX4 cause delayed repair of the DSBs as judged by γH2AX foci.

Recently, it has been demonstrated that NS5B interacts itself forming oligomers, and mutations that disrupt these interactions are lethal for polymerase function.

Alternatively, the ancient hub of the network may accumulate compensatory mutations that allow it to interact better with modern nodes.

108 Other mutations affecting podocyte proteins that interact with the actin cytoskeleton, including α-actinin-4, CD2-associated protein, and synaptopodin have been associated with podocyte injury and FSGS in humans or experimental animals.