Sentence examples for mutations that inhibit from inspiring English sources

However, by combining two genetic mutations that inhibit key molecules involved in insulin signaling, or IIS, and the nutrient signaling pathway know as Target of Rapamycin, or TOR, scientists saw a five-fold extension of longevity, wrote senior author and biologist Pankaj Kapahi. .

Mutations that inhibit interactions also significantly reduce Foxi1 dependent reporter gene activation.

Mutations that inhibit heterochromatin formation suppress variegation, whereas mutations that increase the abundance of heterochromatin enhance variegation.

Mutations that directly impair the development and/or function of alveolar macrophages [50], as well as mutations that inhibit degradation of surfactant within these cells, have been shown to result in alveolar proteinosis and pulmonary dysfunction in both mouse and human [51].

Genetic mutations that inhibit IIS activation prolong lifespan in these organisms, particularly in the female sex.

Haploinsufficiency or mutations that inhibit apoptosis rescue the embryonic lethality and expose the carcinogenic effects (14, 18).

An alternative scenario could be a mutation that inhibits the interaction of the gene with others.

ΔF508 is a processing mutation that inhibits folding in the endoplasmic reticulum and trafficking to the cell surface.

Most surprisingly, the Q153R CPR mutation, a rare disease-causing mutation that inhibits steroidogenic activity, increased the activity of both CYP1A2 and CYP2C19 to 144 and 284%, respectively.

This is achieved by cytoduction, which involves mating donor and recipient yeast in the presence of a kar1 mutation that inhibits efficient nuclear fusion.

A non-conserved substitution (p.Arg200Gln) in the PRKAG3 gene was initially characterized in Hampshire pigs [ 3], and is thought to be a dominant negative mutation that inhibits glycogen degradation.