Sentence examples for mutations that eventually from inspiring English sources

The classic view of how cancer develops is that a single, normal cell accumulates mutations that eventually allow or force it to divide uncontrollably.

Could there be a bacteria or virus that triggers the initial mutations that eventually lead to cancer?

This DNA editing results in the introduction of mutations that eventually render the target genome inactive.

This generalized genetic instability is thought to lead to the accumulation of additional mutations that eventually allow Brca1-deficient cells to undergo neoplastic transformation (reviewed in [ 2]).

The arising of advanced liver cancer in transgenic fish after long-term induction is potentially due to additional mutations that eventually cause an irreversible malignant phenotype.

In breast epithelial cells chronically exposed to estrogens, sub-optimal DNA repair and the resulting genomic instability may lead to accumulation of genetic mutations that eventually drive a cancerous phenotype.

To our interest, evidence suggests that HIV-1 genetic diversity may influence the type and rate of resistance mutations that may eventually emerge upon drug exposure [ 3, 4].

However, stem cells are also key elements in the earliest stages of gastric and colonic cancer, as they form a target for mutations that may eventually lead to the development of the malignant phenotype.

(3) Combined with ongoing association studies in a FL1/DUKsi crossbreeding family the present data will substantially help to identify candidate genes and causative mutations that are eventually responsible for increased fertility performance in mice.

Excessive oxidation of DNA by ROS could be a major cause of DNA damage and genetic instability (32, 33), which leads to accumulation of mutations and deletions that eventually contribute to carcinogenesis.

If these substitutions occur in germ cells, they constitute a heritable mutation that may eventually rise to polymorphic frequencies, hence resulting in a SNP that is methylation associated.