Sentence examples for mutations that establish from inspiring English sources

The coverage for mutations that establish a single gene disorder varies widely among providers.

We used simulations within a standard population-genetic framework to study the fate of pairs of mutations that establish new regulatory connections (see Methods).

The Department of Molecular and Human Genetics at Baylor College of Medicine [ 5] and some of these providers offer testing focused on less common mutations that establish a diagnosis of a single gene disorder.

This is a broad definition of compensatory mutations, because it encompasses not only those mutations that directly counteract a particular deleterious mutation, but also mutations that establish a new neutral network far away from the main network.

The OncoMap platform robustly detected mutations that constitute established markers of response to targeted therapies.

Here, to illustrate the breadth of this phenomenon, we describe five examples of protein-misfolding events that can lead to disease: improper degradation, mislocalization, dominant-negative mutations, structural alterations that establish novel toxic functions, and amyloid accumulation.

Thus, the expected number of independently originated adaptive mutations that successfully establish before the first one has reached fixation is of order (2 s) Ne UAlog(Ne s)/ s = Θ log(Ne s) and, therefore, depends only logarithmically on the selection coefficient of the adaptive allele.

Ma1, and Ma70 are NSCLC cell lines harbouring EGFR mutations that were established at the Kinki University, Osaka, Japan.

MuSiC is a comprehensive mutational analysis pipeline that establishes correlations among mutation sites, genes and pathways.

Given a specified size distribution for antigenic mutations, the average size of antigenic mutations that will successfully establish can be calculated.

Sdc10608 line is a P-element mutation that was established by the BDGD Project and maintained over a balancer (Bal) chromosome [72].