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During that time, it is possible that it has acquired a number of suppressor mutations that enhanced its survival.
We uncovered eleven s euss-modifier (sum) mutations that enhanced the seu-1 phenotype.
We mutagenized seu-1 seeds and visually screened the M2 generation for second site mutations that enhanced the sterility and gynoecial splitting of the seu-1 mutant (Methods).
To advance our knowledge of the involvement of CTR1-mediated ethylene receptor signaling, we performed a genetic screen for mutations that enhanced the constitutive ethylene response in the weak ctr1-10 allele.
Reprogramming of gene expression could occur in response to inhibition of cellulose synthesis during the habituation process or may be associated with or due to the effect of mutations that enhanced resistance to inhibition of cellulose synthesis.
Our results demonstrate that the sc-rtTA activity can be significantly improved by introduction of mutations that enhanced rtTA activity, suggesting that sc-rtTA folds very similarly to rtTA.
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A mutational strategy that combines elimination of buried free cysteines and secondary mutations that enhance thermostability to achieve a substantial gain in functional half-life is described.
Point mutations that inactivate Cas9 nuclease activity are shown in red, and mutations that enhance its fidelity are shown in black.
This variant was engineered to combine mutations that enhance MBP solubility and affinity purification, as well as provide crystal-packing interactions for increased crystallizability.
In contrast, native-like Env trimers fail to activate B cells expressing germline antibodies but elicit bNAbs by selecting for a restricted group of light chains bearing specific somatic mutations that enhance neutralizing activity.
Several genetic screens using a variegating white gene as a reporter have identified mutations that enhance or suppress PEV.
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