Sentence examples for mutations that dominate from inspiring English sources

There is a growing consensus that the genetic component of complex traits may reflect a different spectrum of sequence variants than the missense and nonsense mutations that dominate monogenetic diseases and traits.

At one end of the clonal spectrum, we have mutations of major effect that dominate the fitness of the clone they are adopted by.

Combined with the neutrality plot and ENc- plot, the results suggest that it is natural selection rather than mutation pressure that dominates the SCUB in mtDNA of B. mori.

fans that dominated the grandstands.

Scott Walker that dominates Wisconsin's political terrain.

In contrast to genomic DNA, best-fit models of dinucleotide frequencies in transcribed RNA sequences expressed in the cytoplasm from all organisms were dominated by mutations that eliminated UpA dinucleotides, observations consistent with cytoplasmically driven selection for mRNA stability.

Our results, especially in the various changing trends (most of them are not linear) further validated that mutations (dominated by GC content variations) and selections (dominated by purine content variations) mainly act at the level of nucleotides rather than codons or amino acids in accordance with previous studies [ 12, 41, 52].

Only during the last follow-up period (54 112 months after transmission) sequence evolution was dominated by forward mutations that mainly occurred in epitopes restricted by recipient HLA.

Serial analysis of patient samples showed that one mutation or clone dominates at a time, but new mutations are able to replace previously dominant ones and mutations that fall below the limit of detection are sometimes detectable in subsequent samples (Campbell et al., 2010).

Somewhere among the genetic disparities must lie the mutation or, more probably, mutations that define us.

Evolution depends on mutations that simply don't have direction.