Sentence examples for mutations that deactivate from inspiring English sources

When fully induced, the regulatory system is in principle free to lose regulation by neutral drift: mutations that deactivate the repressor do not affect the growth rate.

The fourth type of event is termed de-exonization, which is the conversion of an internal exon into an internal portion of an intron by mutations that deactivate splicing signals.

The third type of event is termed de-intronization; in this case, sequences are not deleted from the genome, but rather an intronic sequence is converted into an exonic sequence by mutations that deactivate splicing signals.

To test the H840A mutation that deactivates the HNH domain, we also injected sgRNA plasmids into P{nos-Cas9 H840A}attp2 embryos.

In principle, there are two ways by which cancer cells may escape the damage response during cancer progression and therapy: through genetic mutations that cripple the checkpoint pathway, or by hijacking cellular mechanisms that would naturally deactivate the checkpoint.

Mutations that add or change function?

Somewhere among the genetic disparities must lie the mutation or, more probably, mutations that define us.

The truncating mutations are, in fact, clustered as p.W288fs, a four base insertion that deactivates the carboxyl terminus and delocalizes the protein [ 47].

It is, it turns out, a potent antioxidant, a chemical that deactivates free radicals.

A suppressor mutation that creates.

Hutchinson's group went on to develop methods to improve the yield of DXR, from the fermentation process used in its commercial production, not only by introducing dox A encoding plasmids, but also by introducing mutations to deactivate enzymes that shunt DXR precursors to less useful products, for example baumycin-like glycosides.