Sentence examples for mutations that damage from inspiring English sources

Third, Charlesworth [12] showed that if some genes are beneficial at both reproductive and post-reproductive ages, then mutations that damage those genes should be selected against and late-life mortality should be restrained as a result.

However, Ju et al. revealed that DNA mutations that damage normal mitochondrial activity are less likely to be maintained in cancer cells.

Mitochondria are inherited only from mothers, never from fathers, so there is no way to weed out mutations that damage a male's prospects.

In simple terms, the study aims to understand and analyze: a) rules that aid interactions between DNA and certain biomolecules known as transcription factors (that "activate" a gene); and b) rules (mutations) that could potentially damage such interactions.

The second biologically relevant question is whether mutations that facilitate asymmetric damage distribution actually do occur in simple unicellular organisms.

Chronic exposure to genotoxic stress is known to accelerate aging, and mutations that disrupt proper DNA damage responses and interfere with DNA damage repair are associated with premature aging in humans [ 13].

As a powerful approach, in silico bioinformatics analysis could efficiently sort out mutations that are predicted to damage gene function.

Cells with Brca1 mutations that have accumulated DNA damage are therefore allowed to proliferate rather than undergo apoptosis.

By combining classic genetic suppressor screening with high-throughput DNA sequencing, we identify Mre11 mutations that strongly suppress DNA damage sensitivities of sae2∆ cells.

Genotoxicity is induced by chemicals that are mutagenic (agents that increase the rate of mutations) and/or clastogenic (agents that damage DNA structure).

Among birds they have documented reduced longevity and male fertility, smaller brains, and mutations that indicate significant genetic damage compared with the same species in areas of low radiation.