Sentence examples for mutations that convert from inspiring English sources

Mutations that convert the normal c-Myb protein into an oncogenic transforming protein also change the spectrum of genes that it regulates [2], [3].

In other NF-κB proteins, such as c-Rel and RelA, site-directed mutations that convert the natural Cys residue (at the position homologous to Cys67 of Nv-NF-κB) to Ser increase the affinity of the protein for a κB site [12] [15].

One experiment looked at the frequency of mutations that convert tRNA-Tyr into ochre suppressor mutations.

Essential causes often abrogate tumor suppressor function, whereas mutations that convert proto-oncogenes into oncogenes tend to be exacerbating causes.

Mutations that convert Ras into an oncoprotein are found in up to 25% of human tumors [ 15] (http://www.sanger.ac.uk).sanger.ac.uk

Many prophage encoded genes are transcriptionally silent, acquire mutations that convert them into pseudogenes and in time undergo degenerative changes and become phage remnants [ 43].

We were then able to engineer an in silico mutant channel with three point mutations that converted mVDAC1 into a channel with a preference for cations.

Methylcytosine tends to mutate to thymine (T), thus the gradational accumulation of mutation that convert CpG dinucleotides to TpG dinucleotides lead to AT-rich genomes [ 37– 37].

Therefore, we sequenced the MRH2 genomic DNA and found that there was a G to A mutation that converted a conserved 3' splicing site AG (at the end of the 5th intron) to AA (Figure 2A, upper panel).

Sequencing of these genes from osu1-2 revealed that At1g78230 was identical to the reference sequence, and an A to T mutation in the seventh exon of At1g78240 (Figure 6B) resulting in a missense mutation that converts Asn at 560 to Tyr (N560Y).

The catalytic α subunits cannot bind the NPxYR sequence of ApoER2, but a point mutation that converts the arginine residue adjacent to the NPxY motif to a leucine rescued Pafah1b α subunit binding, demonstrating that this residue is critical for coupling the Pafah1b complex selectively with VLDLR.