Sentence examples for mutations that conferred from inspiring English sources

The prevalence of mutations that conferred primary resistance to protease inhibitors (PIs) was only 0.8% at position V82I.

In an attempt to discover factors that might confer increased cell survival following transplantation, we initiated a genetic screen for insertional mutations that conferred resistance to oxidative stress in human myoblasts.

Since one aim of the work was to identify attenuating targets that can serve as the basis for generation of live vaccine candidates, the goal was to avoid mutations that conferred marginal attenuation and therefore the first screen was performed based on the administration of a dose of 1,000 CFU.

We included all drug resistance mutations that conferred low, intermediate or high-level resistance [11].

To identify additional factors required for ABA-responsive inhibition of root elongation, we screened for mutations that conferred ABA-resistant root elongation (AR mutants).

More importantly, a screen of tumors from relapsed patients identified MEK1 mutations that conferred resistance to BRAF inhibition, as well as to MEK inhibitors [ 99].

Mutations that confer higher levels of resistance to SP did not emerge.

In addition, we identify mutations that confer species-specific resistance, or antifolate-specific resistance.

What is less well understood is the evolutionary history of the mutations that confer drug resistance in the H5N1 population.

Scientists have since found other genetic mutations that confer resistance to Gleevec, and companies are now using such information to design drugs to overcome that resistance.

Additionally, we mutate the target of the cancer therapeutic bortezomib, PSMB5, and identify known and novel mutations that confer bortezomib resistance.