Sentence examples for mutations that also from inspiring English sources

Paradoxically, the most ethical research at this time of uncertainty about management of off target mutations that also explores the potential to combat disease and aging is research with firm endpoints for destruction of embryos, that is, destructive embryo research.

We show that H274Y decreases the amount of neuraminidase that reaches the cell surface and that this defect can be counteracted by secondary mutations that also restore viral fitness.

An alternative explanation may be confounding interference from background mutations that also impinge on longevity pathways.

Thus, mutations already known to be associated with virological failure were given more weight than polymorphisms (mutations that also occur occasionally generally without association to antiretroviral treatment).

The authors found a surprising amount of correlated adaptation to "moderate" temperatures surrounding 37°C, suggesting that selection at this temperature had favored mutations that also improved performance at (presumably) physiologically similar temperatures.

Although examples of protein-coding mutations that contribute to phenotypic evolution are well known (e.g., [ 4- 6]), examples of regulatory mutations that also affect phenotypic adaptation are less well known, but no less important (e.g., [ 7- 9]).

Dr Louis Chesler, a paediatric oncologist at the Royal Marsden, said the drug targets a genetic mutation that also occurs in some children with neuroblastoma.

In the worm experiment, published by Leonard Guarente of the Massachusetts Institute of Technology in 2001, the strain of worms used had picked up an extra mutation that also had the effect of prolonging life, the London researchers report.

This is clearly a source-gene mutation that also supports the ordering of NANOGP1 as being older than NANOGP4.

A splice-site mutation in FUS intron 13 leads to C-terminal truncation of the protein (IVS13-2A > G) (DeJesus-Hernandez et al., 2010), and a point mutation in exon fifteen leads to missense mutation R521C(Chio et al., 2011), a mutation that also occurs in fALS.

It has been reported that a gene-trap inserted in intron 1 of the Prep1 gene gave rise to a hypomorphic mutation that also resulted in variable expression of the Prep1 protein and an embryonic lethal penetrance that was dependent on the degree of leakiness of the gene-trap cassette (Ferretti et al. 2006).