Sentence examples for mutations that account from inspiring English sources

Scientists have discovered a trio of genetic mutations that account for nearly 100,000 cases of Alzheimer's disease in Britain today.

The general failure to identify gene mutations that account for genetic inheritance in prostate cancer suggests that it may be appropriate to examine epigenetic mechanism of inheritance.

The T allele of the PHB 3'UTR polymorphism has recently been shown to be associated with an increased risk of breast cancer (ORadj, 2.12; 95% CI, 1.23 3.70) [ 10] in Polish women carrying one of the three common BRCA1 founder mutations that account for approximately 90% of all detected BRCA1 mutations detected in this country [ 11, 12].

This rationale could provide a better means to uncover functionally important mutations that account for FIP.

In closely related, inter-fertile species, genetic analysis can reveal the mutations that account for functional differences, but not their temporal order, and even this level of detail cannot be achieved in more distantly related species.

In several of the remaining cases, the technique helped identify genetic mutations that accounted for some, but not all, of a patient's symptoms; in others it simply determined that none of the identified candidate genes were involved in the patient's illness.

The caveat is that VX-770 is designed to counter one specific genetic mutation that accounts for about 4 percent of cases of cystic fibrosis.

Only two MLH1 deletions had been reported at that time, one of which was a founder mutation that accounted for a large proportion of HNPCC kindreds in the Finnish population (Nyström-Lahti et al, 1995; Mauillon et al, 1996).

Although genetic factors may influence the dominance of pathological involvement to some extent (Al-Chalabi et al., 2012), 95% of patients report no family history of ALS or frontotemporal dementia, and currently have no obvious single genetic mutation that accounts for their disease despite indistinguishable clinical appearances.

Conclusions: The screening of the entire coding region of the ccr5 gene in all ESN did not revealed no other mutations that could account for resistance to HIV-1 infection.

H1N1/09 viruses appear similar to existing swine lineages, which multiple H2H mutations that may account for its capability to transmit among humans.