Sentence examples for mutations suitable for from inspiring English sources

To identify a subset of mutations suitable for further attenuation of W1806, we analyzed effects of E138K and K279M changes on virulence, growth properties, and immunogenicity of derivatized W956, from which chimeric W1806 inherited its biological properties and attenuation profile.

Instead of massively parallel sequencing of primary tumors to identify somatic mutations suitable for AF ascertainment an easier approach is plasma-Seq, as it is independent of pre-knowledge of somatic mutations.

It would seem, however, to be especially useful for genetically tractable organisms such as C. elegans where genomics tools are well developed, but where reverse genetics techniques that can provide heritable mutations suitable for genetic analysis lag far behind.

For UCP3 point mutations suitable primers (5′-CTATGGACGCCTACGGAACCATCGCCAGG-3′ and 5′-CCTGGCGATGGTTCCGTAGGCGTCCATAG-3′ for UCP3R167G or 5′-CAGAACCATCGCCGGGGGGGAAGGAGTCAGG-3′ and 5′-CCTGACTCCTTCCCCCCCGGCGATGGTTCTG-3′ for UCP3RE171/172GG, respectively) exchanged the corresponding codons from AGA to GGA (UCP3R167G) or from AGG GAG to GGG GGG (UCP3RE171/172GG), respectively.

Also, it remains an unanswered question as to whether the mutant stocks with single gene mutations are suitable for functional genomics studies of complex phenotypes, which are controlled by many genes and influenced by the environment (Li et al. 2005).

We used mutation analysis suitable for identification of both dominant and recessive mutations to investigate the sarcomeric gene for cardiac troponin I (TNNI3) in 235 patients with dilated cardiomyopathy.

The above facts motivate us to develop a novel mutation method suitable for the qualitative model space, and we expect that on one hand the features of the original Opt-AiNet mutation operation can be preserved to some extent, and on the other hand after mutation the new antibody is more likely to attain a better position in the search space.

About 5% of the families segregated for albino plants (Additional file 1), which suggested that the mutant population contained sufficient random point mutations and was suitable for screening.

Most of those mutations are not suitable for the life cycle of parasites, and only a few suitable for survival under the conditions of artemisinin selection pressure could be selected.

The development of an IDH1 R132H mutation-specific antibody suitable for immunohistochemistry has largely facilitated detection of mutated IDH1 protein in clinical practice (Capper et al, 2009).

Therefore, H114Y mutation was not suitable for the construction of the rhEPOR ligand.