Sentence examples for mutations suggest a from inspiring English sources

And most mutations suggest a propensity, not a guarantee, for a disease.

Along with MLL1/4, MLL2/3 mutations suggest a dual role for MLL family proteins in oncogenesis, which may depend heavily on cellular context.

In the context of our findings that SigH and SodA suppress host immune responses, these mutations suggest a mechanism by which BCG Pasteur 1173P2 and BCG Danish 1331 evolved to become more immune suppressive and thus more virulent than their predecessors.

These mutations suggest a mechanism involving misinsertion of a base opposite a DNA adduct followed by a slippage and mismatch.

The selection and phenotypes of these mutations suggest a functional role for the C-terminal moiety of SltB.

Loss-of-function mutations suggest a role for PFLU0458 as a c-di-GMP degrading enzyme, which is also supported by data from Pseudomonas aeruginosa, where the orthologue PA5017 (dipA, pch) lacks DGC activity, but is proficient for phosphodiesterase activity (Roy et al., 2012).

In contrast, when six oncogenic mutations are required for cancer (C = 6), α50% ranges from 11 30 (Supplementary Table S1), in the lower range of commonly observed values of mutation rate increase due to mutator mutations, suggesting a predominance of mutator pathways, in that most mutator mutations would then correspond to α>α50%.

In contrast, when six oncogenic mutations are required for cancer (C = 6), α50% ranges from 11 30 (Supplementary Table S1), in the lower range of commonly observed values of mutation rate increase due to mutator mutations, suggesting a predominance of mutator pathways.

Remarkably, the cells of participants younger than 65 were free of the same mutations, suggesting a link to the aging process, known as cellular senescence, which Dr. Attardi continued to study until recently.

These modifications are possible by single point mutations, suggesting a potential yield of a more infectious virus.

In some INAD/NBIA cases, both alleles were affected by early frame shift and stop codon mutations, suggesting a complete loss of protein function [1], [6].