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Well-designed behavioral screens are focused to find mutations specific to a particular neural system.
Passenger mutations specific to particular mouse strains can distort experimental outcomes.
We identify a subset of mutations specific to the B strain, which allows us to investigate the selection pressures affecting duplicated genes in this allotetraploid.
Thus, the NA activity of the 2009 isolates is still effectively inhibited by zanamivir, consistent with the lack of NA mutations specific to all the isolates that are less sensitive to zanamivir.
This is probably due to the short evolutionary distance separating these two clades (Fig. S2), which makes unlikely the fixation by positive selection of mutations specific to one clade with respect to the other.
The majority of the 13 Indian isolates grouped in the globally most widely circulating H1N1pdm clade 7. Further, correlations of the mutations specific to clade 7 Indian isolates to viral fitness and adaptability in the country remains to be understood.
Similar(19)
The treatment--so far only examined in test tubes--targets a gene mutation specific to the cancer cells, leaving healthy cells unharmed.
Therefore the activation of RET seems to be a somatic cell mutation specific to human thyroid carcinomas.
In our patient, PCR sequencing showed the β 74 GCC to GAC point mutation (Gly to Asp) mutation specific to Hb Shepherds Bush.
The BRCA1 5382insC mutation, specific to Ashkenazi and Russian populations, was found twice in our study group, representing a possible founder mutation in the Turkish population.
A major gene or causal mutation specific to each breed (DGAT1 and casein variant) could explain the good results obtained for the within-breed model.
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