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Nearly half of known ADLTE-related LGI1 mutations are nonsense and frameshift mutations, some of which are predicted to cause a decreased abundance of mutated mRNA transcripts because of their degradation by nonsense-mediated decay.
Adult cells that have been reprogrammed into stem cells harbor a number of genetic mutations, some of which appear in genes that have been linked to cancer.
One important example is mutation breeding: seeds are exposed to chemicals and radiation that generate a pool of seeds with different mutations, some of which may be beneficial.
Scientists suspect that these faulty genes may have also collected new mutations, some of which could be beneficial under certain circumstances.
In addition, the MG isolates display other specific mutations, some of them affecting the head of HN.
Colorectal cancer progresses through an accumulation of somatic mutations, some of which reside in so-called "driver" genes that provide a growth advantage to the tumor.
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Like the swarms of proofreading enzymes that monitor DNA for mutations, some tens of thousands of regular Wikipedians constantly revise and polish the growing repository of information.
Swap mutation, arithmetic mutation, jump mutation, uniform mutation and creep mutation are some of the well-known mutation operators.
Beside the RDL mutation, some of the genes over-transcribed could be associated to dieldrin resistance.
Founder populations are known to harbor unique mutations and some of the mutations rare in other populations can also show enrichment in them.
Oncogenic Ras mutations are some of the most frequently detected driver mutations in human cancer.
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CEO of Professional Science Editing for Scientists @ prosciediting.com