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Somatic mutations should have the highest immunological impact.
However, it does suggest that all mutations should have arisen many times during our experiments.
Thus, all types of mutations should have an equal chance to be fixed [ 35].
Even in regions with lower coverage, novel mutations should have 20 or more reads (and k-mers) covering them.
Indeed, if late mutations played little role, then accumulation of mutations should have been markedly decelerating with age.
Since combustion of DF led to higher PM emissions the number of mutations should have been corrected for the difference of PM between the fuels.
Similar(46)
So it sounds like women who test positive for the mutation should have both their breasts and their ovaries removed as soon as possible, right?
Had the two arms of the study not been carried out in parallel, future researchers might have travelled up an expensive and time-consuming blind alley.Another question is why such a disastrous mutation should have spread so widely in Africa.
This Cdc12 mutation should have had little effect if the pocket of Cdc11(G29D) is nucleotide-free.
This suggests that the second mutation should have a greater score as it has to be acquired a few times independently during the evolution process.
For the exomes we have analyzed, average coverage is approximately 80 100×, which means that a novel, heterozygous mutation should have 40 50× coverage.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com