Sentence examples for mutations resistant to from inspiring English sources

We then describe our analysis of the data, and calculate the number of mutations resistant to all possible combination treatments according to the number of drugs, their types and concentrations.

Point mutations resistant to the siRNA treatment were introduced by DpnI-mediated site-directed mutagenesis.

Prolonged use of LAM will almost invariably lead to the development of viral mutations resistant to the drug.

To establish stable cell lines, HeLa Tet-On cells were transfected with pTRE2-Myc-based plasmids encoding RNAi-resistant Myc-PICH4M (contain silent mutations resistant to siPICH4).

[ 12] In the pre-transplant setting prolonged use of LAM will almost invariably lead to the development of viral mutations resistant to the drug.

Understanding differences in patterns of discontinuation for treatment-experienced and for treatment-naïve patients is needed because multiple treatment exposures increase the probability of accumulating mutations resistant to specific medications, raising the risk of MDR TB.

From this convention, we can use the data to extract the types of point-mutations resistant to each drug, according to their category of concentrations.

L3 protein consisted of about 210 amino acids and its mutation resistant to pleuromutilin centered to C-terminal.

Src, Abl, and PDGFR can be inhibited by the oral small molecule inhibitor dasatinib, which is already registered for use in chronic myeloid leukemia with BCR-ABL mutation, resistant to imatinib.

The presence of a mutation in gyrA that resulted in an amino acid change at position 81 was associated with an approximately two fold increase in MIC to ciprofloxacin with 52.4% (11 out of 21) of isolates with this mutation resistant to ciprofloxacin.

It is highly probable that the occurrence of the resistance associated with EMT depends on the cellular context since we did not observe EMT in UM-UC-14 bladder cell lines with FGFR3 mutation resistant to AZD4547, BGJ398, and PD173074, respectively (our unpublished data).