Sentence examples for mutations representing the from inspiring English sources
These values were multiplied by the colony-size ratio of sck2 relative to ade6 mutations, representing the fitness of the query.
We started the analysis by identifying human missense pathological mutations representing the wild-type residue at the homologous site in non-human mammals, following a previously reported methodology [ 12].
The result was a curated set of 43 mutations representing the most exhaustive to date status of identified and characterized TDP-43 gene mutations, further referred to as 'TDP-43 mutations core set'.
Nucleophosmin-1 (NPmutationsions represent the most frequent gene alteration in acute myeloid leukemia (AML).
These mutations represent the first example of altering arrestin specificity via enhancement of the arrestin-receptor interactions rather than selective reduction of the binding to certain subtypes.
Oncogenic KRAS mutations represent the largest genomically defined subset of lung cancer, and are associated with activation of the RAS/RAF/MEK/ERK pathway.
Nucleophosmin mutations of exon 12 (NPmutationsons) represent the most frequent molecular aberration that can be found in patients with acute myeloid leukaemia (AML) and can be detected in about 35% of AML patients.
Gain-of-function of erythropoietin receptor (EPOR) mutations represent the major cause of primary hereditary polycythemia.
PEST domain mutations represent the majority of mutations found in mouse T cell lymphomas and are thus good representatives.
LRRK2 mutations represent the most common cause of PD with clinical and neurochemical features that are largely indistinguishable from idiopathic disease.
Although we cannot rule out contributions of linked variation to the melanic phenotypes possessed by mice from New Hampshire and Alaska, given the likely effects of the Δ125kb and Q65term mutations and the known effects of null Agouti alleles in other taxa, it is very likely that these mutations represent the causative variation underlying these melanic phenotypes.
