Sentence examples for mutations represented the from inspiring English sources
Patients with double CEBPA mutations represented the combination of C- and N-terminal mutation types.
We found that compound heterozygous mutations represented the majority of the mutation types in all of the patients.
The number of driver mutations is likely to differ significantly between tumours; the requirement for 20 driver mutations represented the estimated maximal driver mutation burden in colorectal cancer (Sjöblom et al. 2006) and is in accordance with previous models (Beerenwinkel et al. 2007).
Nucleophosmin-1 (NPmutationsions represent the most frequent gene alteration in acute myeloid leukemia (AML).
These mutations represent the first example of altering arrestin specificity via enhancement of the arrestin-receptor interactions rather than selective reduction of the binding to certain subtypes.
Oncogenic KRAS mutations represent the largest genomically defined subset of lung cancer, and are associated with activation of the RAS/RAF/MEK/ERK pathway.
Nucleophosmin mutations of exon 12 (NPmutationsons) represent the most frequent molecular aberration that can be found in patients with acute myeloid leukaemia (AML) and can be detected in about 35% of AML patients.
Gain-of-function of erythropoietin receptor (EPOR) mutations represent the major cause of primary hereditary polycythemia.
PEST domain mutations represent the majority of mutations found in mouse T cell lymphomas and are thus good representatives.
LRRK2 mutations represent the most common cause of PD with clinical and neurochemical features that are largely indistinguishable from idiopathic disease.
Although we cannot rule out contributions of linked variation to the melanic phenotypes possessed by mice from New Hampshire and Alaska, given the likely effects of the Δ125kb and Q65term mutations and the known effects of null Agouti alleles in other taxa, it is very likely that these mutations represent the causative variation underlying these melanic phenotypes.
