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Liao et al. engineered NIH3T3 cells to express the range of separate mutations represented in the squamous cell lung cancer TGCA [ 15].
The sum of the relative weights of mutations represented in the IAS list was 70%, meaning that mutations of the IAS list contributed the most to calculate the first principal component.
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Failure to accomplish this could result in a mutation represented in the pool below the level of detection.
Another approach to studying the potential consequences of E487K mutation represented in the ALDH2*2 carrying East Asians is the use of transgenic mice overexpressing ALDH2*2.
The model showed that H246N and Y251S mutations represented reductions in the size of the side-chains of the NH2-terminal strand.
We also considered the possibility that some of the mutations represented variations in the GL sequence due to the hypothetical presence of an unusual VH1-69 allele in subject SjS2.
The KIT exon 9 mutations represent mainly in-frame tandem duplication, AY502-503dup.
Class II mutations (represented by specific fusion genes in the original model) impair haematopoietic differentiation and subsequent apoptosis.
Out of 13,912 SNP changes, homozygous mutations represented as 1/1 or 0/0 only in single plant constituted 11%% and heterozygous mutations represented as 0/1 only in single plant constituted 89 %.
Overall, these results indicate that nearly all mutations are represented in the plasmid mutant libraries.
These results indicate that the vast majority of codon mutations are represented in the plasmid mutant libraries.
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