Sentence examples for mutations represent potential from inspiring English sources

In this manner, the protein products of genes SS/SL to cancer-causing mutations represent potential drug targets.

The assay developed by O'Donnell et al. (2014) appears useful for rapid identification of mutations representing potential therapeutic targets in tumors with complex clonal evolution.

By both reconstitution and mutational analysis of the pedigree, six unaffected subjects were shown to bear the M404V mutation, representing potential asymptomatic gene carriers whose circulating levels of alkaline phosphatase were recently assessed as still within the normal range.

Toxicology data suggest that generation of reactive oxygen species (ROS) and the resulting mutations represent another potential carcinogenic mechanism.

These alternate SNP positions could represent potential new mutations.

PIK3CA mutation and FGFR1 amplification both represent potential targets for personalized squamous cell lung cancer therapy, and it may therefore be important to analyze both these gene alterations in clinical practice.

Therefore, mutation and sequencing error rates can represent potential confounding factors.

In conclusion, somatic mutations in PTPRT, BCL11B, SLIT2 and NRP1 represent potential genetic cause for LGL leukemia.

This gene family was selected because PTPs are expected to exert tumor suppressive function and thus represent potential targets of inactivating mutations in DNA mismatch repair deficient tumors.

These represent potential loss of function (LOF) mutations.

Interestingly, three genotype E isolates had the sM133T mutation, which could possibly compromise antibody neutralization and may represent potential vaccine escape mutants [ 52].