Sentence examples for mutations remains speculative from inspiring English sources

Until these studies are performed, the optimal treatment for patients with PCP, who have had substantive exposure to sulfa prophylaxis and who are therefore likely to have DHPS mutations, remains speculative.

HT29 is mutated in APC and in the absence of evidence; it remains speculative if APC mutation modulates PAK1 expression in these cells.

Theoretically, such a diversity of B-ALL subclones may also occur in mice, but given the short latency (<4 weeks) and the lack of pressure by the immune system, it remains speculative whether similar mutations can be observed in our murine model of tumour initiation.

Whether this difference would remain or would be adjusted away in multivariable analyses remains speculative.

However, this defect was not accompanied by increased pri-miRNA levels [ 57], and furthermore p53 mutations are infrequent in AML [ 58], so that such a mechanism remains speculative at present.

It remains speculative how the genomic changes arise at the corresponding environmental response gene loci, simply by random mutation and sexual recombination, or by another internal spontaneous mutator?

The exact purpose of the Antikythera mechanism remains speculative, however.

It's important to stress that this work remains speculative.

This however remains speculative.

The mechanism of the delivery remains speculative.

The cause of this underestimation remains speculative.