Sentence examples for mutations remains difficult from inspiring English sources

Thus, the step from QTL to causative mutations remains difficult.

Unlike direct PKD1 mutation testing, where it remains difficult to assign pathogenicity to some variants, the majority of PKD2 sequence variants can be assigned as likely or highly likely to be pathogenic [ 12, 13].

Despite this progress, it remains difficult to identify causative mutations in the genomes of many patients.

This illustrates that, in regulatory regions, it remains difficult to identify causative mutation among all candidates.

Overall, the method provides a reliable distinction between different shapes of the distribution of arising mutations, although distinguishing between α values lower than 2 remains difficult.

But their task remains difficult.

"For now the situation remains difficult".

Assessing the program's effect remains difficult.

Of course, the security situation remains difficult.

So the choice remains difficult to explain.

And so levelheadedness remains difficult.