Sentence examples for mutations relevant to from inspiring English sources

Such numerical guides, however, were incomplete or low magnitude for Fanconi anemia pathway (FANC) gene mutations relevant to cancer in FANC-mutation carriers (heterozygotes).

He and other researchers have since identified a variety of other mutations relevant to A.L.S. "The problem is that these mutations pertain to a very small number of patients," he said in an interview.

Rather than hunting separately for five groups of patients with the mutations relevant to each drug, the researchers will use a test from Foundation Medicine, a company that screens patients for abnormalities in 236 genes linked to cancer.

To evaluate the potential of an integrated clinical test to detect diverse classes of somatic and germline mutations relevant to pediatric oncology, we performed three-platform whole-genome (WGS), whole exome (WES) and transcriptome (RNA-Seq) sequencing of tumors and normal tissue from 78 pediatric cancer patients in a CLIA-certified, CAP-accredited laboratory.

The consumer therefore needs to ensure that the mutations relevant to his or her ethnicity are tested.

For much of that time, he explored neural circuits in mice with mutations relevant to schizophrenia, anxiety disorders, and depression, trying to get at how particular mutations lead to corresponding, abnormal behaviors.

H221Y, a novel NNRTI-resistance mutation relevant to NVP, emerged in all the six patients.

Candidate genes could then be followed in recombinant chromosomes to allow for the identification of the mutation relevant to the defect in compensatory proliferation.

Thus only a subset of mutations is relevant to the reversion under selection.

To pinpoint the mutations most relevant to LNZ resistance, we sequenced a new S. pneumoniae strain, 1974M1, and two S. pneumoniae LNZ-resistant transformants generated by whole genome serial transformation of LNZ-sensitive strains with genomic DNA isolated from highly LNZ-resistant mutants.

For a range of mutation rates relevant to the observed level of homozygosity at microsatellite loci, the product rule may significantly underestimate the 13-locus MP.