Sentence examples for mutations relevant for from inspiring English sources
The cut-off values for the resistance mutations relevant for this study are summarized in Table 2.
Since the C. elegans knockoutswere created by random mutagenesis and might bear additional mutation(s), we used two different deletion alleles of ATX-3; both were backcrossed five times to wild-type animals (N2 strain), to exclude other mutations relevant for the phenotype, as previously described [19].
Genomic CTC analysis can also reveal gene mutations relevant for therapy resistance.
All subjects were screened for 11 FLG mutations relevant for the study population.
Recent advances in genome sequencing technologies provide unprecedented opportunities to characterize individual genomic landscapes and identify mutations relevant for diagnosis and therapy.
Next-generation sequencing technologies provide unprecedented opportunities to characterize individual genomic landscapes and identify mutations relevant for diagnosis and therapy for Mendelian disorders, complex diseases and cancers.
Our approach for identifying mutations relevant to cancer development specifically maps somatic mutations to the individual domains in which they occur, resulting in a more accurate measure of enrichment of mutations at the domain level.
Such numerical guides, however, were incomplete or low magnitude for Fanconi anemia pathway (FANC) gene mutations relevant to cancer in FANC-mutation carriers (heterozygotes).
Are mtDNA mutations relevant in normal aging?
The first mechanism (resistance through mutations) is relevant for resistance to β-lactam antibiotics (e.g. cephalosporins and carbapenems) and quinolones (e.g. ciprofloxacin), but is of no relevance for resistance based on large genetic elements such as vancomycin resistance in enterococci and methicillin resistance in Staphylococcus aureus.
Though most of these background mutations are not relevant for the initiation of leukaemia, few relevant mutations may occur and give advantage to the cell, which then undergoes transformation into a LSC and initiates leukaemia.
