Sentence examples for mutations ranging from from inspiring English sources

PIK3CA is the most frequently mutated oncogene in human breast cancers and shows activating mutations ranging from 10% in the triple-negative subgroup to 40% in the hormonal receptor-positive/ERBB2-negative subgroups.

CRISPR/Cas9 (CRISPR-associated protein 9) genome editing has been used to correct disease-causing DNA mutations ranging from a single base pair to large deletions in model systems ranging from cells in vitro to animals in vivo.

To determine the in vivo function of PiT1, we targeted the PiT1 locus by homologous recombination in ES cells and generated an allelic series of mutations ranging from mild impairment to elimination of PiT1 function.

Similar to the spectrum of hematological findings associated with telomerase mutations, ranging from isolated macrocytosis to acute myeloid leukemia, liver disease was heterogeneous in severity and pathology among telomerase-mutation carriers.

Sensitivity varied according to mutations, ranging from 0.6% to 15%, with a mean of 3.3%.

A series of small deletion mutations, ranging from 1 base pair (bp) to 22 bp, was identified.

The degree of penetrance of this EVE neural phenotype is variable: all Df(1 446-20 embryos show at least two missing RP2s whereas Ppt1A179T and Ppt1S77F point mutations range from 32 50%.

The number of somatic mutations ranged from 743 to 3910.

These somatic mutations range from severe insertion deletion and chain termination mutations to mild missense mutations.

The phenotype associated with dominant ABCC8/KCNJ11 mutations ranges from asymptomatic macrosomia to persistent HH in childhood.

In contrast, the frequency of p53 mutations ranged from 44.2% to 48.7% in virus-unrelated HNSCCs.