Sentence examples for mutations raise a from inspiring English sources

These mutations raise a woman's risk for breast and ovarian cancer, as well as a man's risk of prostate cancer, because they disable proteins that repair DNA damage that can result in additional cancer-spurring mutations.

This mutation raises an important question – how much ACE (tissue and/or blood) is appropriate to maintain healthy conditions?

Myriad is known for its test for genetic mutations that raise a woman's risk of getting breast cancer.

If nonsynonymous mutations raise the fitness, their rate will be increased by positive selection (d N >d S ).

These mutations raise the possibility that additional drugs that target CML cells through alternative mechanisms to Bcr-Abl have the potential to be successful in treating imatinib-resistant CML patients (Druker et al, 2001).

However, the finding that the K- ras 4A/4B ratio is also reduced in CRC cell lines that lack K- ras activating mutations raises the possibility that a regulated switch in alternative splicing of the K- ras proto-oncogene may also have a causal role in tumour progression [ 12].

Other guidelines, such as National Comprehensive Cancer Network [ 12], have made no specific distinction between different PALB2 mutations but do raise a general caution around the interpretation of testing for mutations in PALB2 and other "moderate penetrance" breast cancer predisposition genes, especially as part of panel tests.

Our results on the abnormal electrophysiological properties and increased drug sensitivity of cardiac cells derived from an asymptomatic KCNH2 R176W mutation carrier raise an important issue about LQT2 and also a new challenge, as well as a possibility, for the pharmaceutical industry.

The highest frequency of p53 mutations raises the possibility that p53 mutagenesis is a predominant factor for breast cancer development in this low-risk Japanese group, whereas in other cohorts different mechanisms are likely to account for the higher proportion of breast cancer.

The paucity of gene mutations raises questions about the appropriateness of the currently used screening approaches.

Her heart problems could not be linked to any of the known mutations, raising the possibility that this SCN5A variation might somehow contribute to the irregularity.