Sentence examples for mutations provides an from inspiring English sources

However, the existence of a substantial subset of chronocoordinate mutations provides an alternative explanation.

The availability of information on over 10 000 laboratory-induced mutations provides an opportunity to (1) measure the performance of computational tools for accuracy in diagnosing laboratory mutations and (2) compare them with the performance observed for a large collection of naturally occurring human variants with and without disease implications.

Our finding of de novo mutations provides an explanation for many of the seemingly puzzling features that have been described in the past including the sporadic nature, the highly variable phenotype and the association with increased paternal age (Fletcher and Foley, 1993).

Thus, the presence of tumor-specific mutations provides a potential link to predicting methylation status.

A high frequency of LGRs among the MSH2 mutations provides a rationale for a MLPA screening of the Slovakian HNPCC families prior scanning by DNA sequencing.

The combination of these two mutations provides a model that demonstrates a severe neuromuscular phenotype and accurately mimics the symptoms of human muscular dystrophies.

However, the distribution of distances found between adjacent candidate SNV mutations provides a measure of caution against the assumption that a single mutation is responsible for the mutant phenotype.

In summary, the protein pocket-based prioritization of somatic mutations provides a promising approach to uncover the putative cancer drivers and anticancer drug response biomarkers in the post-genomic era for cancer precision medicine.

The presence of germline mutations provides a potential source to identify genetic targets for early intervention of tumorogenesis process in BRCA1+ carriers long before tumor formation in breast cells, for which there are currently limited options besides preventive surgery.

The clonal expansion of somatic mitochondrial DNA mutations provides a common mechanism for the PEO, ptosis and myopathy seen in several mitochondrial DNA maintenance disorders, and our data suggest that the same is occurring in SPG7.

Due to this high prevalence, it is thought that gene amplification, rather than point mutations, provides a pool of preexisting variation allowing bacterial populations to adapt to various stresses, such as antibiotic resistance or growth on unusual carbon sources (2).