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Interestingly, the AB allele frequencies suggest that AB underwent a recent population bottleneck (Additional file 1: Figure S5f), and thus we infer that these mutations provided a strong selective advantage, allowing the subpopulation to expand rapidly.
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The identification of the lethal mutations provided an indication of the types of mutations that might be induced genome-wide.
Because each lineage of Y chromosomes carries its own signature set of DNA changes, these mutations provide a perfect system for tracking male genealogies, and that is what Dr. Sykes looked for in the cotton swabs mailed back to him.
Further analysis revealed that rbf1 mutations provide a sensitized genetic background for Psc-induced developmental defects.
Mutations provide a continuous source of variation in natural populations, on which natural selection can act.
Thus, the presence of tumor-specific mutations provides a potential link to predicting methylation status.
The novel collagen mutations provide a valuable addition to the set of known mutations available for studying genotype phenotype relationships.
PIK/AKT mutations provide a cell with the abilities to evade apoptosis and survive hypoxic and avascular conditions.
In this work, we demonstrate how anticodon mutations provide a rapid mechanism to alter the tRNA pool.
A high frequency of LGRs among the MSH2 mutations provides a rationale for a MLPA screening of the Slovakian HNPCC families prior scanning by DNA sequencing.
All three mutations provide a strong fitness benefit under Pi-limitation and in BW4218 or BW4227, the rpoS mutation was the dominant fitness determinant in the isolate (fig. 3 A ).
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