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Because each lineage of Y chromosomes carries its own signature set of DNA changes, these mutations provide a perfect system for tracking male genealogies, and that is what Dr. Sykes looked for in the cotton swabs mailed back to him.
Further analysis revealed that rbf1 mutations provide a sensitized genetic background for Psc-induced developmental defects.
Mutations provide a continuous source of variation in natural populations, on which natural selection can act.
PIK/AKT mutations provide a cell with the abilities to evade apoptosis and survive hypoxic and avascular conditions.
In this work, we demonstrate how anticodon mutations provide a rapid mechanism to alter the tRNA pool.
The novel collagen mutations provide a valuable addition to the set of known mutations available for studying genotype phenotype relationships.
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This mutation has been detected exclusively in B-ALL and almost always in association with mutations in the CRLF2 gene 15, thereby suggesting that these mutations provide an advantage to B-lineage commitment, perhaps by inducing a weaker signal that preferentially activates only one signaling pathway.
Thus, the presence of tumor-specific mutations provides a potential link to predicting methylation status.
A high frequency of LGRs among the MSH2 mutations provides a rationale for a MLPA screening of the Slovakian HNPCC families prior scanning by DNA sequencing.
The outcome of the study considerably extends the growing list of pathogenic MEN1 mutations providing a consequential insight into phenotypic heterogeneity and in the expression of individual mutations.
The combination of these two mutations provides a model that demonstrates a severe neuromuscular phenotype and accurately mimics the symptoms of human muscular dystrophies.
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