Sentence examples for mutations produced in from inspiring English sources

The fact that GRN mutations produced in mice do not display all the features of the human disorder has limited progress towards effective treatments for FTD.

It is hard to reconcile an omnipotent, classical theistic God with all of the monstrosities and chance mutations produced in nature, but the general orderliness of the natural world is just as difficult to reconcile with there being no Orderer or Persuader at all.

Our findings demonstrate in the monkey that hypoxanthine guanine phosphoribosyltransferase (hprt) mutations produced in vivo can be detected using technique originally worked out using human cells; cynomolgus monkeys were chosen to avoid many of the complications encountered in studying humans.

Overall, these results highlight how mutations produced in the laboratory that determine product profile differences also exist in nature and do result in the evolution of altered TPS product profiles between species or genotypes.

Then, to ascertain whether these SNPs were spontaneous mutations produced in the individual infected cells and its immediate progeny or, in contrast, were parental sequence variants (i.e., already present in the inoculum), we compared these SNPs with those found in the viral stock by ultra-deep sequencing.

Hong et al. [ 47] analyzed the mutations produced in strains evolved with improved galactose utilization and concluded that the phenotypic changes observed in these evolved strains were the result of mutations in regulatory systems, which produced the overexpression and activation of some metabolic routes.

The target site was chosen to be close to the beginning of the open reading frame in order that frameshift mutations produced would result in a non-functional protein.

npp-5, npp-12, and npp-14 mutations produced 100% sterility in mel-28 mutants.

Both mutations produced modest increases in extinction coefficient and quantum yield, and the S179T mutation also accelerated maturation.

Nonsense mutations segregated at appreciable frequencies in TLR09B in L. montandoni, the more common of these mutations produced a stop codon in position 48, indicating that the respective allele does not encode a functional protein.

The mutations produced an inadvertent stop signal in the gene, causing the cell to make a cut-down version of the gene's normal protein, the researchers report in Nature Genetics.