Sentence examples for mutations predispose specifically from inspiring English sources

Similarly, BRCA1 mutations predispose specifically to breast and ovarian cancer and hypermethylation is limited to cancer of these tissues [ 40].

However, this does not explain why BRCA1 or BRCA2 mutations predispose so specifically to breast and ovarian cancer nor why BRCA1 or BRCA2 insufficiency can have profound effects on processes such as proliferation and differentiation.

Testa, J. R. et al. Germline BAP1 mutations predispose to malignant mesothelioma.

Smith MJ, Wallace AJ, Bennett C, et al. Germline SMARCE1 mutations predispose to both spinal and cranial clear cell meningiomas.

Germ-line PTEN mutations predispose to breast cancer in association with CD, although the signs of CD may be subtle.

The mutations predispose women to both breast and ovarian cancer, and a woman with a mutation who has already had cancer in one breast also has a higher than average risk of developing cancer in the other breast.

Our data suggest SHANK3 mutations predispose to autism, at least partially, by inducing an Ih channelopathy that may be amenable to pharmacological intervention.

MUTYH mutations predispose to recessively inherited colorectal polyposis and cancer.

BRCA1/2 mutations predispose to early-onset breast cancer, especially after oral contraceptive (OC) use and pregnancy.

Heterozygous ACTA2 mutations predispose to thoracic aortic aneurysm disease (TAAD) [ 6].

ACTA2 mutations predispose to development of aortic aneurysms and early onset coronary and cerebrovascular disease.