Sentence examples for mutations play a from inspiring English sources

To determine whether mitochondrial DNA mutations play a role in the development of age related maculopathy (ARM).

In the case of depression, MTHFR mutations play a significant role as they impact the methylation cycle, that produces many neuro-transmitters.

Induced chromosomal and gene mutations play a role in carcinogenesis and may be involved in the production of birth defects and other disease conditions.

Scientists have wondered whether somatic, or non-inherited, mutations play a role in aging and brain degeneration, but until recently there was no good technology to test this idea.

Interestingly, 7% of MSS/MSI-L CRC bore PIK3CA mutations, suggesting that PIK3CA mutations play a role in both subsets of CRC but might represent a more important oncogenic event for the development/progression of MSI CRC than MSS CRC.

PIK3CA mutations were detected within the MSI and microsatellite stable (MSS) CRC phenotypes suggesting that PIK3CA mutations play a role in the development/progression of both subsets of CRC (Samuels et al., 2004; Velho et al., 2005).

In cancer, germline mutations play an important role in the establishment of tumor pathways.

Study of mutagenesis has assumed importance due to the fact that mutations play an important role in carcinogenesis [ 6].

Taken together, in contrast to HBV infection, viral escape mutations play an essential role for viral persistence in HCV infection.

Somatic mutations play an important role in cancer initiation and progression, as well as in prognosis [ 9].

Our results strongly suggest that K- ras -2 mutations play an important role in the pathogenesis of VC-associated HCC.