Sentence examples for mutations participated in from inspiring English sources
MQB performed and analyzed the sequencing of ovarian cancers for TP53 mutations, participated in the generation of gene expression signatures, and in writing the manuscript.
Overall, 53 out of 93 (57%) patients were allocated to 58 clinical trials between October 2012 and June 2013; 29 out of 53 patients (55%) who participated in clinical trials had trials suggested based on a relevant mechanism of action for the identified 'actionable' mutation (Table 5), whereas 29 out of 63 (46%) patients with identified actionable mutations participated in matched trials.
If both deleterious and advantageous mutations participate in tumor initiation, then we find an intermediate optimum for the compartment size.
De Benedetti et al (1994) reported that frameshift mutation of APC gene was predominant in polypoid adenomas, with APC mutations participating in progression of exophytic adenomas.
In particular, novel mutations participate in the NNRTI resistance may be more complex (≥3 NNRTI resistance mutations) than the first-generation NNRTIs resistance [ 9].
Further investigation will be required to determine how often loss of function mutations participate in a variety of evolutionary processes, ranging from cancer to the formation of new species and forms of biological organization.
The objective of this study was to evaluate the treatment effects of ivacaftor on patient-reported symptoms and health-related quality of life (HRQoL) as reported by patients with CF 12 years of age and older with the G551D- CFTR mutation participating in the STRIVE study.
METHODS: Serum samples of 66 individuals with a CDKN2A germline mutation who participated in the pancreatic surveillance program (5 cases, 61 controls) were obtained following a standardized protocol.
Seven BRCA mutation carriers participated in a GMC in our pilot study.
JAL: Supervised the BRCA1/2 mutation detection, participated in the design and coordination, and helped to draft the manuscript.
However, in the subset of patients with a germline BRCA1 or BRCA2 mutation who participated in a Phase II study of olaparib monotherapy, no confirmed objective responses were observed in the eight patients with breast cancer [ 14].
