Sentence examples for mutations outlined in from inspiring English sources

We believe that the oncogenes that define the subtypes in Table 1 are capable of serving as the dominant oncogene and putative point of intervention for therapy, whereas the oncogenes and tumor suppressor genes that define subtypes in Table 2 play a supportive role and typically co-exist with the mutations outlined in Table 1.

However, because patients with mutations in familial pancreatic cancer genes, such as those described earlier, are relatively uncommon among patients newly diagnosed with this disease, agents that target pancreatic cancer based on more common somatic driver mutations outlined in Table 2 would be applicable to a greater proportion of patients.

It should still be outlined in yellow.

These were then ranked into two groups based on the mass spectrometric profiles and the likelihood that these represent true mutations referred to as conservative and aggressive "calls" which comprised 10% (12/115) and 90% (103/115) of possible mutations, respectively (outlined in Figure 1 and Additional file 1 Table S2).

To ensure that effect of the R1039A mutation is indeed measured in trans, we additionally disabled the catalytic site of the R1039A mutant by the H1061N mutation, as outlined in Figure 4a.

Of course, we would predict that mutator lineages are also more likely to produce low-fitness genotypes (the 'double-edged sword' of mutation as outlined in our introduction), but these are presumably removed by purifying selection.

If no progress in the pbest value is observed for an elapsed period of DELTA, carry out the mutation of a particle using the mutation strategy as outlined in the 'Particle swarm optimization' section provided that DELTA is greater at random number between zero and maximum time of no progress (MAXT).

Screening of the CMMB for gene-specific point mutations followed the protocol outlined in Figure 1.

The crosses employed in the screens for EMS induced dumpy mutations in defined isoallelic backgrounds are outlined in Table 2.

The principle of this approach, which relied on the error-prone nature of reverse transcription (error rate between 10−4 and 10−5) [34] to generate mutations during virus replication and is outlined in Fig. 1A.

The first reason for this is that, as outlined in table 1 outside of silent mutations, new mutations will most frequently lead to loss of functions, and will usually be recessive.