Sentence examples for mutations outcome of from inspiring English sources

Some of single base deletions could come from classical or altered NHEJ repair of DSBs [ 20], but more likely they represent along with other point mutations outcome of processing base oxidative damage.

Moreover, we present data suggesting a) a differential impact of non-codon 12 KRAS mutations on outcome of cetuximab-treated patients of Greek ethnic origin, b) a KRAS mutation-independent predictive significance of EREG mRNA expression, c) a strong predictive value of AREG mRNA expression in KRAS wild type patients.

To analyze the main clinical features, genetic mutations, and outcomes of patients of the French Congenital Central Hypoventilation Syndrome (CCHS) Registry.

We retrospectively reviewed the clinical characteristics, cytogenetic profiles, molecular gene mutations and outcomes of patients in our AML cohort.

We conducted a retrospective study to investigate the clinical aspects, cytogenetic abnormalities, molecular gene mutations and outcomes of adult AML patients with CNS involvement.

Correlation between single mutations and the outcome of the therapy was used to select relevant mutations for the model.

This study was designed to investigate the impact of LMV resistance mutations on the outcome of ETV rescue therapy in LMV-refractory patients.

Many studies have shown the association of HBV genotype/subgenotype and specific mutations with clinical outcome of HBV, though the role of HBV genotypes in response to antiviral therapy is still uncertain [42], [43], [44].

However, the impact of KRAS and BRAF mutations on clinical outcome of patients with locally advanced CRC are unknown.

We performed this study to address the possible impact of additional gene mutations on the outcome of APL.

Although BRCA1 and BRCA2 were identified in 1994 and 1995, the influence of germline BRCA1/ BRCA2 mutations on the outcome of women with breast cancer has remained undefined.