Sentence examples for mutations or lack from inspiring English sources

Another possibility is that APC mutations, or lack thereof, could make a significant difference.

TNBC tumors have the poorest prognosis and tend to grow and spread to other parts faster than other cancers and often harbor BRCA1 mutations or lack of expression.

Besides mutations or lack of expression of BRCA molecules, deficiency of several other proteins involved in the HR pathway may sensitize cancer cells to PARPi.

When the signal for growth arrest is missing, owing to mutations or lack of appropriate signals (e.g. on a hydrophilic surface or in rich medium), polar growth continues and mycelium develops.

This still does not satisfy our third query, i.e., why are the associations specifically confined to this subgroup of colon cancer patients whose tumors are characterized by activating KRAS mutations, and not truncating APC mutations or lack of MLH1 expression?

Unliganded DAF-12 also promotes longevity in animals subjected to daf-2 RNAi but shortens life span in animals harboring daf-2 mutations or lacking a germline.

Even if SERCA can be specifically targeted, such inhibition does not effect on T-ALL cells with activated Myc mutations or lacking NRR region [ 37].

Later, in 2007, after 7.3 years of follow-up of the Netherlands cohort study, linoleic acid, the most abundant polyunsaturated fatty acid in the diet, was still associated with increased risk of colon tumors with only a KRAS mutation and no additional truncating Apc mutation or lack of MLH1 expression (Weijenberg et al., 2007).

The effect of mutation or lack of CK1ε on Wnt signaling remains to be tested.

However, linoleic acid showed an association with increased risk of colon tumors with only an activated KRAS mutation and no additional truncating APC mutation or lack of MLH1 expression.

Some of the cells in the F0 frog may maintain their functions because they contain an in-frame mutation or lack a mutation, whereas other cells may lose the expression of the target gene because of premature translational termination or nonsense-mediated mRNA decay caused by an out-of-frame mutation.